出生于低生育率夫妇的孩子,他们的情况如何? 来自研究的证据
Nadine Iman Schottler1, Alastair G Sutcliffe2
1Population, Policy and Practice Unit, University College London, London, UK.
Archives of disease in childhood
|April 8, 2024
概括
通过辅助生殖技术 (ART) 出生的1000多万名儿童正在进入第三代. 虽然一些风险仍然存在,但最新的研究表明长期健康问题,对ART概念的整体风险降低.
科学领域:
- 生殖医学 生殖医学
- 儿科健康 儿科健康
- 公共卫生 公共卫生
背景情况:
- 辅助生殖技术 (ART) 已经导致全球超过1000万例分娩.
- 通过ART怀孕的个体的长期健康结果需要持续评估.
- 了解不育本身对ART结果的影响至关重要.
研究的目的:
- 总结来自越来越多的关于人工智能孕育个体的文献中的关键健康信息.
- 识别与ART相关的持续和新出现的健康风险.
- 为未来的研究方向提供建议.
主要方法:
- 系统审查和综合有关ART健康结果的现有文献.
- 对围产,新生儿,神经,心脏代谢,内分泌和瘤风险趋势的分析.
- 在ART怀孕的儿童中评估神经发育结果.
主要成果:
- 出生早产,低出生体重,先天性形和脑的风险增加仍然存在,但显示减少.
- 新出现的证据表明潜在的长期心脏代谢和内分泌问题.
- 几乎没有报告儿童恶性瘤或神经发育异常的风险增加.
结论:
- 虽然与ART怀孕相关的一些风险已经减少,但长期健康监测至关重要.
- 未来的研究应该解决诸如不孕症之类的混因素,并完善对比组.
- 确保ART怀孕个体的长期健康和福祉是首要任务.
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