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Updated: Jun 29, 2025

Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation
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Published on: October 25, 2024

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一个GITRL-mTORC1-GM-CSF正循环促进了原发性Sjögren综合征中的致病性Th17反应

Yuzhou Gan1, Haotian Zhou1, Yixue Guo1

  • 1Department of Rheumatology and Immunology, Beijing Key Laboratory for Rheumatism and Immune Diagnosis (BZ0135), Peking University People's Hospital, Beijing, China.

Arthritis & rheumatology (Hoboken, N.J.)
|April 8, 2024
PubMed
概括

葡萄糖皮质类药物诱导的瘤亡因子受体超级家族相关蛋白质连接体 (GITRL) 通过促进致病性Th17反应,加剧了原发性Sjögren综合征 (pSS). 针对GITRL提供了对pSS的潜在治疗策略.

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