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Updated: Jun 29, 2025

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
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同时抑制癌症和野生型RAS- GTP用于癌症治疗

Matthew Holderfield1, Bianca J Lee1, Jingjing Jiang1

  • 1Revolution Medicines, Redwood City, CA, USA.

Nature
|April 8, 2024
PubMed
概括

一种新的药物RMC-7977在治疗各种RAS突变癌症方面具有前景. 这种RAS(ON) 多选择性抑制剂针对多种RAS变体,包括KRAS,NRAS和HRAS,具有难以治疗的瘤的潜力.

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