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人类INSC的一个错误突变导致了外围神经病变

Jui-Yu Yeh1, Hua-Chuan Chao2,3,4, Cheng-Li Hong1

  • 1Graduate Institute of Physiology, National Taiwan University, Taipei, Taiwan.

EMBO molecular medicine
|April 8, 2024
PubMed
概括

在INSC基因的突变导致Charcot-Marie-Tooth病类型2 (CMT2) 通过扰乱外周神经系统 (PNS) 中的PAR3/INSC/LGN复合体. 微管稳定剂药物可能为这种神经退行性疾病提供治疗方法.

关键词:
可以注射的可注射.查尔科特玛丽牙神经病变2型微管稳定剂 微管稳定剂尸体消亡 (necrosis) 是一种致死症.自己的感觉 (proprioception)

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