使用TIDieR报告检查清单描述试验招募干预措施的内容:系统方法审查
Natasha Hudek1, Kelly Carroll1, Seana Semchishen1
1Clinical Epidemiology Program, Ottawa Hospital Research Institute, 501 Smyth Road, Box 201B, Ottawa, ON, K1H 8L6, Canada.
BMC medical research methodology
|April 8, 2024
概括
招聘干预研究往往缺乏关于定制和忠诚等关键要素的详细报告. 改善复杂干预措施的描述对于改善临床试验参与者招聘至关重要.
科学领域:
- 临床试验方法论 临床试验方法论
- 医疗保健服务研究 医疗服务研究
- 干预科学 干预科学
背景情况:
- 临床试验参与者招聘仍然是一个重大挑战.
- 招聘策略是具有多个组成部分的复杂干预措施.
- 干预描述和复制模板 (TIDieR) 检查清单可以评估干预报告.
研究的目的:
- 评估招聘干预研究中TIDieR检查清单项目报告的程度.
- 为了识别如何描述招聘干预组件的变化.
主要方法:
- 评估了122个随机的,嵌套的招聘干预研究.
- 利用了来自Cochrane审查和临床试验研究在线资源数据库的数据.
- 应用了TIDieR检查清单标准,并开发了用于分析的描述变量.
主要成果:
- 大多数TIDieR项目是可报告的,但裁剪和忠实性很少被详细说明.
- 在一个时间点 (90%) 进行的信息干预 (55%) 是常见的.
- 研究小组 (59%) 在临床环境 (41%) 中经常提供干预措施.
结论:
- 基于TIDieR的变量有效地描述了招聘干预的核心元素.
- 报告干预过程中的元素,如持续时间和真实性是不一致的.
- 进一步的研究应该探索TIDieR变量,以改善成功招聘干预措施的报告.
更多相关视频
06:28E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
Published on: August 1, 2019
8.3K
00:04A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
Published on: September 20, 2019
10.7K
相关概念视频
01:11Clinical Trials: Overview
2.9K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
2.9K
01:16Clinical Trials
6.7K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
6.7K
02:07Blind Procedures
10.6K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
10.6K
01:11Blinding
2.4K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
2.4K
01:56Ethics in Research
23.0K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
23.0K
01:21Methods of Documentation III: PIE
1.4K
Problem-intervention-evaluation (PIE) is a systematic approach to documentation used in healthcare settings for clinical decision-making and patient care planning. It is a structured approach to organizing patient data based on problems, interventions, and evaluations. Here's a breakdown of its key features and considerations:
1.4K