美国骨和矿物质研究协会关于骨折风险临床算法的工作组报告
Sherri-Ann M Burnett-Bowie1, Nicole C Wright2, Elaine W Yu1
1Endocrine Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, United States.
概括
骨折风险工具中的种族和种族调整可能会加剧健康不平等. 一项审查发现这些调整几乎没有理由,而是建议基于人口的模型. 未来的研究需要多样化的队列和社会决定因素数据.
科学领域:
- 骨质疏松症的研究研究.
- 临床算法开发开发的临床算法
- 关于健康公平性的研究.
背景情况:
- 临床算法中的种族和种族调整可以使健康不平等延续下去.
- 美国骨和矿物研究协会 (ASBMR) 成立了一个工作组,评估美国骨折风险评估工具 (US-FRAX).
研究的目的:
- 系统地审查US-FRAX的性能,并没有种族/种族调整来预测骨折.
- 评估种族和种族对不同人群中骨折预测准确性的影响.
主要方法:
- 来自妇女健康倡议 (WHI) 和骨质疏松性骨折研究 (SOF) 的六项研究的系统综述.
- 在10年内预测主要骨质疏松性骨折 (MOF) 和部骨折时,分析了US-FRAX的表现.
- 评估曲线下的面积 (AUC) 在种族和种族群体之间的歧视.
主要成果:
- 群体主要是白人,这限制了代表性不足的群体的稳定分析.
- 没有骨矿物密度 (BMD) 的美国-FRAX在年轻的WHI队列中,在种族群体中对MOF的歧视有限.
- 没有BMD的US-FRAX在较老的WHI队列中高估了MOF.
结论:
- 有有限的证据支持在骨折风险预测中进行种族和种族调整.
- 建议基于人口的骨折预测模型,包括健康的社会决定因素.
- 倡导有代表性的研究队伍和关于种族,种族和社会决定因素的标准化数据收集.
关键词:
弗拉克斯 (FRAX) 是一个骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折,骨折.骨折风险评估工具 骨折风险评估工具在健康方面存在差异.骨质疏松症是一种骨质疏松症.种族和民族是什么更多相关视频
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