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Updated: Oct 21, 2026

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一种经过完全验证的LC-MS/MS方法,用于在NSCLC患者的血样本中量化bevacizumab,以及它对治疗药物监测的影响

Bo Li1, Meng Yang2, Xiaoxue Wang1

  • 1Department of Pharmacy, China-Japan Friendship Hospital, Beijing 100029, P.R. China.

Oncology letters
|April 9, 2024
PubMed
概括

对贝瓦西祖马布的治疗药物监测在癌症治疗中至关重要. 一种经过验证的超高性能液体染色学双重质谱法,可以准确地测量非小细胞肺癌患者的贝瓦西祖马布水平.

关键词:
这是bevacizumab的治疗方法.这是一种单克隆抗体.纳米表面和分子导向的有限蛋白质分解.治疗药物监测 治疗药物监测超高性能液体色谱学 双重质谱学 质谱学

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Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...