在COVID-19患者的紧急手术后的术后结果:一项雄心勃勃的匹配队列研究
Sunaina T Karna1, Zainab Ahmad1, Pooja Thaware1
1Anesthesiology, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.
Cureus
|April 9, 2024
概括
患有冠状病毒疾病 (COVID-19) 的急诊手术的患者面临30天死亡风险的12.3倍. COVID-19状态显著增加了ARDS和败血症等术后并发症.
科学领域:
- 外科手术的结果
- 传染性疾病 传染性疾病
- 麻醉学 麻醉学
背景情况:
- 关于印度次大陆冠状病毒病 (COVID-19) 患者的手术结果的数据有限.
- 了解接受紧急手术的COVID-19患者的术后风险对于患者管理至关重要.
研究的目的:
- 与匹配的对照组相比,评估接受紧急手术的COVID-19患者的术后结果.
- 确定COVID-19的紧急手术患者中术后死亡率的预测因素.
主要方法:
- 在印度中部的一家三级护理医院进行了观察性匹配队列研究 (2021年7月 - 2022年6月).
- 接受紧急手术的COVID-19阳性患者 (病例) 与COVID-19阴性患者 (对照组) 相匹配.
- 病例与对照群之间的30天死亡率和术后并发症的比较.
主要成果:
- COVID-19阳性外科队列显示,与对照组相比,30天后术后死亡风险增加了12.3倍.
- COVID-19 状态与急性呼吸道应急综合征 (ARDS),败血症,休克和高血糖症的更高率相关.
- 死亡率的预测因素包括手术前呼吸障碍,ARDS,更高的ASA-PS类,升高的SOFA和快速SOFA得分,以及异常的和肝功能测试.
结论:
- 严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 感染在紧急手术患者中显著增加了术后并发症和30天死亡率.
- 早期识别风险因素对于改善这一脆弱的外科患者群体的结果至关重要.
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