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Updated: Jun 29, 2025

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癌症中的PIAS家族:从基本机制到临床应用

Xiaomeng Li1, Azhar Rasul2, Farzana Sharif2

  • 1KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, Guangdong, China.

Frontiers in oncology
|April 9, 2024
PubMed
概括

激活STATs的蛋白抑制剂 (PIAS) 调节基因转录,并与癌症有关. 准PIAS蛋白及其SUMOylation通路为抑制癌症生长提供了一个潜在的治疗策略.

关键词:
饼是为了饼.这就是SUMOylation的作用.转录因子 (STAT) 的激活剂信号传感器 信号传感器转录因子转录因子

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