对右心辅助装置的柔性叶片的最佳弹性模量进行研究,以支持单心室生理学的患者
Tong Chen1, Xiaoming Cheng2, Xudong Liu3
1Academy for Engineering and Technology, Fudan University, Shanghai, China.
Frontiers in cardiovascular medicine
|April 9, 2024
概括
这项研究为单心室患者开发了一种柔性叶片右心辅助装置. 数字模拟发现灵活的叶片的最佳弹性模量在40-50MPa之间,平衡性能和安全.
科学领域:
- 生物医学工程 生物医学工程
- 心血管器械 心血管器械
- 计算流体动力学的流体动力学.
背景情况:
- 单心室生理学在缓解外科手术后的循环功率中提出了挑战.
- 提出了一种具有灵活叶片的新型右心脏辅助装置,用于循环支持.
- 调查这些柔性叶片的最佳弹性模量对于设备的有效性至关重要.
研究的目的:
- 为了确定右心辅助器件中柔性叶片的最佳弹性模量.
- 评估叶片弹性的对设备性能的影响,包括压力上升,血液溶解和血栓形成的风险.
- 通过数值模拟来比较柔性刀片与刚性刀片的性能.
主要方法:
- 使用了一种单向流体结构相互作用 (FSI) 模拟方法.
- 结合计算流体动力学 (CFD) 和有限元素分析 (FEA) 进行了代.
- 在各种弹性模块和旋转速度中评估了血压升高,血液溶解风险和血栓形成风险.
主要成果:
- 灵活的叶片通常导致压力上升低于刚性叶片,除了8000rpm的40MPa弹性模量外.
- 弹性叶片的弹性模量增加导致了更高的压力上升.
- 灵活和刚性刀片之间的血液溶解和血栓形成风险没有显著差异.
结论:
- 叶片变形通常会降低螺旋的功能,旋转速度是血液溶解和血栓形成风险的关键因素.
- 灵活叶片的最佳弹性模量被确定为40-50MPa.
- 这种弹性模量范围为单心室生理学患者提供了循环辅助和生物相容性之间的平衡.
更多相关视频
06:18Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery
Published on: December 6, 2024
508
09:29Using Digital Image Correlation to Characterize Local Strains on Vascular Tissue Specimens
Published on: January 24, 2016
9.4K
相关概念视频
Bending of Members Made of Several Materials
148
In analyzing a structural member composed of two different materials with identical cross-sectional areas, it is crucial to understand how their distinct elastic properties affect the member's response under load. The analysis involves assessing stress and strain distributions using the transformed section concept, which accounts for variations in material properties.
Hooke's Law determines stress in each material, stating that stress is proportional to strain but varies due to each...
Hooke's Law determines stress in each material, stating that stress is proportional to strain but varies due to each...
148
Strain and Elastic Modulus
3.6K
The quantity that describes the deformation of a body under stress is known as strain. Strain is given as a fractional change in either length, volume, or geometry under tensile, volume (also known as bulk), or shear stress, respectively, and is a dimensionless quantity. The strain experienced by a body under tensile or compressive stress is called tensile or compressive strain, respectively. In contrast, the strain experienced under bulk stress and shear stress is known as volume and shear...
3.6K
Relation between Poisson's ratio, Modulus of Elasticity and Modulus of Rigidity
264
Deformation occurs in axial and transverse directions when an axial load is applied to a slender bar. This deformation impacts the cubic element within the bar, transforming it into either a rectangular parallelepiped or a rhombus, contingent on its orientation. This transformation process induces shearing strain. Axial loading elicits both shearing and normal strains. Applying an axial load instigates equal normal and shearing stresses on elements oriented at a 45° angle to the load axis.
264
Members Made of Elastoplastic Material
97
The behavior of elastoplastic materials under bending stresses, particularly in structural members with rectangular cross-sections, is crucial for predicting material responses and understanding failure modes. Initially, when a bending moment is applied, the stress distribution across the section follows Hooke's Law and is linear and elastic. This distribution means the stress increases from the neutral axis to the maximum at the outer fibers, up to the elastic limit.
As the bending moment...
As the bending moment...
97
Hooke's Law
383
Hooke's law, a pivotal principle in material science, establishes that the strain a material undergoes is directly proportional to the applied stress, defined by a factor called the modulus of elasticity or Young's modulus.
383
