分子补充可以减少运动诱导的氧化应激在健康的成年人吗? 一个系统的审查和元分析
Yiting Li1, Renjie Bing1, Meng Liu2
1College of Sports Medicine and Rehabilitation, Beijing Sport University, Beijing, China.
Frontiers in nutrition
|April 9, 2024
概括
分子 (H2) 补充剂可提高健康成年人的抗氧化能力,特别是在间歇性运动期间. 然而,它并不能直接显著降低运动引起的氧化应激水平.
科学领域:
- 运动生理学 运动生理学
- 氧化压力研究研究 氧化压力研究
- 分子疗法分子疗法
背景情况:
- 运动引起的氧化应激会损害神经生理功能,降低运动表现.
- 分子 (H2) 以其选择性自由基清除特性而闻名.
- 之前对H2对运动诱导的氧化应激的影响的研究显示出混合的结果,表明潜在的"双重效应".
研究的目的:
- 系统地审查和分析H2对健康成年人运动诱导的氧化应激的影响.
- 量化评估H2对氧化应激标志物和运动后抗氧化能力的影响.
主要方法:
- 在五个数据库中进行了系统的文献搜索,使用与,氧化应激和随机对照试验相关的关键词.
- 包括六项研究,包括七项实验和76名参与者.
- 干预设计在H2的施用形式 (水,洗,气体),时间 (运动前,运动期间,运动后) 和剂量 (单剂,多剂) 方面有所不同.
主要成果:
- 与安慰剂相比,H2补充剂没有显著改变运动诱导的氧化应激水平 (d-ROMs) (SMD = -0.01,p = 0.94).
- 与安慰剂相比,H2显著改善了抗氧化潜在能力 (BAP) (SMD = 0.29,p = 0.03).
- 亚组分析表明,与连续运动相比,间歇性运动中使用H2的抗氧化能力在间歇性运动中得到更大的改善 (SMD = 0.52,p = 0.02).
结论:
- 补充H2有效地提高了健康成年人的抗氧化能力,特别是在间歇性炼期间.
- 2似乎没有直接减少运动诱导的氧化应激标志物.
- 建议进行进一步的严格研究来证实这些发现,并探索最佳的H2干预策略.
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