在2型糖尿病患者中,老年营养风险指数,骨矿物质密度和身体成分之间的关联
Xiao-Xiao Zhu1, Kai-Feng Yao2, Hai-Yan Huang3
1Department of Pediatrics, The Second Affiliated Hospital of Nantong University, First People's Hospital of Nantong City, Nantong 226001, Jiangsu Province, China.
World journal of diabetes
|April 9, 2024
概括
2型糖尿病 (T2DM) 的营养不良与较低的骨矿物质密度 (BMD) 和骨肌肉质量有关. 老年营养风险指数 (GNRI) 可以帮助评估T2DM患者的这些风险.
科学领域:
- 老年学是一门学科.
- 代谢障碍 代谢障碍 代谢障碍
- 营养科学 营养科学
背景情况:
- 2型糖尿病 (T2DM) 是一个日益严重的公共卫生问题,特别是在老年人中.
- T2DM患者经常患有骨质疏松症和肉症,增加骨折和残疾风险.
- 在T2DM中营养,肉类和骨质疏松症之间的相互作用仍然未得到充分研究.
研究的目的:
- 研究2型糖尿病患者的营养状况,骨矿物质密度 (BMD) 和身体组成之间的关联.
- 在这个人群中确定影响BMD和骨肌肉质量的因素.
主要方法:
- 一项涉及689名T2DM患者的横截面研究.
- 使用老年营养风险指数 (GNRI) 评估营养状况.
- 通过双能X射线吸收计 (DXA) 评估的骨矿物质密度 (BMD) 和身体成分.
- 多变量回归分析确定了与BMD和骨肌肉质量指数相关的因素.
主要成果:
- 较高的GNRI与年轻的年龄相关,较低的HbA1c,增加的BMD和更大的尾骨肌指数 (ASMI).
- 在所有部位,包括腰椎和大腿部,即使在调整后,GNRI也与ASMI,总体脂肪和BMD积极相关.
- 低瘦身量指数和特定的原标记与减少的BMD有关.
结论:
- 低GNRI表示的营养状况差,与T2DM患者的ASMI和BMD降低有关.
- 在T2DM中,GNRI和DXA是评估营养状况,身体组成,骨健康和身体表现的宝贵工具.
- 早期的营养干预可能对管理T2DM的骨健康和肉症至关重要.
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