在膀癌MRI中,ADC值的体积测量是否能达到更高的诊断性能?
Nesma Elsayed Elshewy1, Adel Ali Ramadan1, Wael Mohamed Sameh2
1Diagnostic and Interventional Radiology Department, Alexandria Faculty of Medicine, Alexandria, Egypt.
Acta radiologica (Stockholm, Sweden : 1987)
|April 9, 2024
概括
膀癌MRI中的体积显微扩散系数 (ADC) 测量提供了与感兴趣区域 (ROI) 方法相比较的诊断性能. 从ROI获得的最小ADC值是临床实践中推的.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 膀癌MRI中的明显扩散系数 (ADC) 值对于评估瘤的侵略性和侵入性至关重要.
- 整个瘤体积测量在膀癌症评估中越来越受到关注.
研究的目的:
- 为了比较体积ADC测量的诊断性能与选的兴趣区域 (ROI) 方法在膀癌.
- 为了确定体积ADC测量是否显著改善临床实践中的ROI方法.
主要方法:
- 50名膀癌患者的前性研究,由两名放射科医生进行评估.
- 使用体积和ROI方法测量的平均和最小ADC值.
- 通过类内相关系数评估读者间协议;使用ROC曲线评估有效性.
主要成果:
- 对于两个ADC测量方法,观测者之间有很好的共识.
- 体积测量结果显示,ADC平均值和最小值在统计学上有显著差异 (P <0.00001).
- 根据ROI的最小ADC显示瘤等级和肌肉入侵预测的最高准确度,但AUC差异在统计学上并不显著. ADC值没有显著预测淋巴血管入侵 (LVI).
结论:
- 在膀癌中选择的ROI和体积ADC测量方法都产生不同的值,但具有可比的诊断性能.
- 准确的ROI采样是关键,对于常规临床使用,最好使用ROI衍生的最小ADC值.
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