在使用下定位器进行睡眠内镜期间上呼吸道折叠性的修改:在打和阻塞性睡眠呼吸暂停患者中进行的研究
Patricia Fernández-Sanjuán1,2, Marta Alcaraz3, Gabriela Bosco1,4,5
1Sleep Respiratory Disorders Unit, Hospital Universitario La Zarzuela, 28023 Madrid, Spain.
Journal of clinical medicine
|April 9, 2024
概括
一个下前进装置 (MAD) 模拟器减少了在睡眠内镜期间的上呼吸道缩性,在患有打和阻塞性睡眠呼吸暂停 (OSA) 的患者中. 这个工具有助于识别个人化治疗计划的剩余崩.
科学领域:
- 睡眠医学 睡眠医学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 呼吸系统医学 呼吸系统医学
背景情况:
- 部推进装置 (MADs) 治疗与睡眠相关的呼吸障碍,患者反应各异.
- 药物诱导睡眠内镜 (DISE) 越来越多地用于预测MAD治疗的成功.
- 了解DISE期间的上呼吸道缩性对于患者的选择至关重要.
研究的目的:
- 在DISE期间使用可定位的MAD模拟器评估上呼吸道折叠性变化.
- 在接受DISE的不同患者群体中评估MAD模拟的有效性.
主要方法:
- 包括104名患有简单打和阻塞性睡眠呼吸暂停 (OSA) 的患者.
- 在DISE期间,VOTE尺度评估了气道崩,有或没有MAD模拟器.
- 进行了DISE以分析各种上空气道水平的可折叠性.
主要成果:
- 在MAD模拟下,在打者中减少了软 palates和耳鼻的崩.
- 轻度OSA患者表现出减少的舌头底部崩.
- 中度/重度OSA患者在所有呼吸道水平上经历了显著的改善.
- 剩余的崩发生在小喉,口喉,上喉和舌头.
结论:
- 在所有患者群体中,MAD模拟器有效地降低了上呼吸道缩性.
- 使用MAD模拟器的DISE识别了残留崩,指导了联合治疗策略.
- 由于对MAD治疗的反应变化,个性化的患者选择是必不可少的.
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