高分辨率直肠测量作为希尔施普隆病的查工具:全面的回顾性分析
Oliver Sowulewski1, Magdalena Bubińska1, Agnieszka Zagierska1
1Department of Paediatrics, Gastroenterology, Allergology & Paediatric Nutrition, Medical University of Gdańsk, 80-210 Gdańsk, Poland.
Journal of clinical medicine
|April 9, 2024
概括
高分辨率阳门测量 (HR-ARM) 显示出在幼儿中查赫斯普朗格病 (HD) 的前景. 虽然对两岁以下的患者有效,但它的准确性在老年儿童中下降,因此需要进一步研究以获得更广泛的应用.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 手术创新 在外科创新.
- 诊断成像 诊断成像 诊断成像
背景情况:
- 希尔施普朗格病 (HD) 诊断在儿科患者中具有挑战性.
- 黄金标准,直肠吸管活检 (RSB),是侵入性的.
- 对于早期检测HD,需要使用非侵入性查方法.
研究的目的:
- 评估高分辨率门测量 (HR-ARM) 作为希尔施普隆病 (HD) 的非侵入性查工具的有效性.
- 评估不同儿科年龄组的HR-ARM表现.
主要方法:
- 对136名怀疑患有HD的患者 (2018-2022) 的回顾性分析.
- 患者分为多层次的年龄组:≤12个月,≤24个月和>24个月.
- 分析了HR-ARM结果的灵敏度,特异性,NPV和PPV.
主要成果:
- HR-ARM证实了16例HD病例,敏感度为93.75%,特异性为89.47%.
- 在2岁以下的患者中观察到高诊断性能.
- 在年龄较大的儿童中发现有效性降低,可能是由于慢性便秘并发症.
结论:
- HR-ARM是一种有前途的非侵入性疾病查工具,特别是在年幼的儿童中.
- 在老年儿科人群中存在局限性,需要进一步调查.
- 对HR-ARM的标准化协议,特别是对直抑制反射的标准化协议,对于优化HD诊断至关重要.
关键词:
在 ARM 的 ARM 里.在这里,我们可以看到HD HD HD HD.人权事务高级专员-ARM.春病是春病的一种疾病.这种疾病叫做aganglionosis.不同的对比性阴囊.高分辨率的直肠测量仪.更多相关视频
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