患有后COVID抑郁症的患者的神经认知变化
Marina Khodanovich1, Anna Naumova2, Daria Kamaeva1,3
1Laboratory of Neurobiology, Research Institute of Biology and Biophysics, Tomsk State University, 36 Lenina Ave., Tomsk 634050, Russia.
Journal of clinical medicine
|April 9, 2024
概括
后COVID抑郁症显著损害认知功能,如记忆和处理速度,在男性和女性中观察到明显的影响. 了解这些性别特异性认知缺陷对于COVID-19后个性化抑郁症治疗至关重要.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 传染性疾病 传染性疾病
背景情况:
- COVID-19与抑郁症和认知障碍有关.
- 神经心理缺陷是SARS-CoV-2感染的常见后果.
- 后COVID抑郁症 (PCD) 需要进一步调查其认知影响.
研究的目的:
- 评估被诊断患有后COVID抑郁症 (PCD) 的患者的认知表现.
- 为了比较PCD患者,康复COVID-19个体和健康对照之间的认知功能.
- 在COVID-19和抑郁症的背景下识别认知衰退的预测因素.
主要方法:
- 对71名COVID后患者进行了神经心理测试.
- 参与者包括PCD组 (n=25),无PCD组 (n=46),康复的COVID-19对照组 (n=18) 和健康的对照组 (n=19).
- 评估的认知领域包括记忆,注意力,处理速度和嗅觉功能.
主要成果:
- 与对照组相比,PCD患者在MoCA,WMT,SCWT和TMT中表现出显著的认知障碍.
- 发现了性别特异性缺陷:患有PCD的男性在注意力和记忆力方面的表现较差;患有PCD的女性总体MoCA得分较低,处理速度较慢.
- 两组之间没有发现嗅觉功能 (斯尼芬棒测试) 的显著差异.
结论:
- 在PCD的认知衰退受到直接的COVID-19影响和抑郁症介导因素的影响,包括男性性别和COVID-19的严重程度.
- 研究结果强调,在个性化抑郁症治疗策略中考虑性别和COVID-19之前的严重程度的重要性.
- 神经心理测试对于在COVID-19后患有抑郁症的人群中表征认知缺陷至关重要.
关键词:
在 COVID-19 疫情中,这就是MoCA MoCA.斯特鲁普颜色词汇测试 文字测试步道制作测试 步道制作测试单词记忆测试 单词记忆测试认知障碍是一种认知障碍.抑郁 抑郁症 抑郁症 抑郁症 是一种长时间的COVID.大型抑郁症主要是抑郁症.在COVD-19后的病情.更多相关视频
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