COVID-19 感染是一种多机体性疾病吗? 专注于SARS-CoV-2的肺外感染
Gauthier Duloquin1,2, Thibaut Pommier2,3, Marjolaine Georges4,5
1Department of Neurology, CHU Dijon-Bourgogne, 21000 Dijon, France.
Journal of clinical medicine
|April 9, 2024
概括
严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 导致COVID-19,这是一个系统性感染,影响肺部以外的多个器官. 本综述详细介绍了非肺部表现及其对疾病预后的影响.
科学领域:
- 传染性疾病 传染性疾病
- 病理生理学 病理生理学
- 系统表现的系统表现
背景情况:
- 冠状病毒疾病2019 (COVID-19),由SARS-CoV-2引起,于2019年12月出现.
- 最初被认为是肺损伤,COVID-19现在被理解为系统性感染.
- 疫情已成为一个世纪以来最重要的全球卫生危机.
研究的目的:
- 为 COVID-19 的非肺部参与提供全面的概述.
- 阐明系统性影响的潜在病理生理机制.
- 描述非肺部表现的临床表现.
主要方法:
- 科学文章和案例报告的文献综述.
- 专注于受到SARS-CoV-2影响的器官系统的研究分析.
- 综合有关病理生理学和临床发现的信息.
主要成果:
- SARS-CoV-2 影响多个器官,包括心脏,血管内皮和中枢神经系统.
- 观察到血液静止,脏和胃肠道的异常.
- COVID-19呈现出各种不同的临床表现,严重程度和分布各不相同.
结论:
- COVID-19是一种全身性疾病,广泛涉及器官.
- 非肺部表现有显著影响疾病的过程和预后.
- 了解这些系统性影响对于管理COVID-19患者至关重要.
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