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Updated: Jul 27, 2026

Loss- and Gain-of-function Approach to Investigate Early Cell Fate Determinants in Preimplantation Mouse Embryos
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在小鼠早期胚胎发育过程中,增强剂衍生的RNA的动态格局

Hua Yu1, Jing Zhao2, Yuxuan Shen3

  • 1Westlake Genomics and Bioinformatics Lab, Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou 310024, China; School of Life Sciences, Westlake University, Hangzhou 310024, China; Westlake Institute for Advanced Study, Hangzhou 310024, China; School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Institute of Life Sciences, Nanchang University, Nanchang 330031, China.

Cell reports
|April 9, 2024
PubMed
概括

增强剂衍生RNAs (eRNAs) 对基因表达至关重要. 这项研究揭示了它们在小鼠早期胚胎中的独特特征,并确定了MZGAe1,这对胚胎基因组激活和发育至关重要.

关键词:
CP: 发育生物学科普:分子生物学 分子生物学科普:干细胞研究

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