从两个方程中估计的脉冲波速度值之间的相关性在健康和心血管风险人口中
Marco Av Silva1,2, Ana Ps De Oliveira3, Ana Cs Queiroz4
1Division of Cardiology, Department of Internal Medicine, Federal University of the Triângulo Mineiro, Uberaba, Brazil.
PloS one
|April 9, 2024
概括
计算估计脉冲波速度 (ePWV) 的两个方程显示了几乎完美的相关性. 无论使用办公室或24小时的门诊血压测量来评估心血管风险,这一发现都是正确的.
科学领域:
- 心血管生理学心血管生理学
- 生物医学工程 生物医学工程
- 医学统计 医学统计
背景情况:
- 存在方程来估计脉冲波速度 (ePWV) 使用血压 (BP) 和年龄.
- ePWV是心血管事件的预测指标,可能会超越带带PWV.
- 该研究旨在比较不同的ePWV计算方程之间的相关性.
研究的目的:
- 评估两个不同的方程之间的相关性,以计算估计的脉冲波速度 (ePWV).
- 评估从办公室BP和24小时门诊BP测量中得出的ePWV值的一致性.
- 为了确定年龄和平均BP对ePWV计算的影响.
主要方法:
- 使用办公室BP (MBPOBP) 和24小时门诊BP (MBP24-hBP) 的平均BP (MBP) 计算ePWV.
- 分析了1541人 (1374人有风险因素,167人健康) 的数据.
- 使用一致性相关系数 (Pc) 和多层回归模型来评估相关性和影响.
主要成果:
- 在两个ePWV方程之间观察到几乎完美的相关性 (Pc ≈ 0.99),用于办公室和门诊BP.
- 平均ePWV值在不同组的两个方程之间没有显著差异.
- 年龄和MBP是强有力的预测因素,解释了所有计算的ePWV中超过99.5%的差异.
结论:
- 对ePWV的两个评估方程显示了高度一致的结果.
- 使用办公室或门诊BP测量,ePWV计算是可靠的.
- 年龄和平均血压是ePWV的主要决定因素,突出了它们在心血管风险评估中的重要性.
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