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Updated: Jun 28, 2025

Hybrid PET/MRI Imaging of Alzheimer's Disease Based on 18F-AV-1451
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针对阿尔茨海默病的新型多功能塔克林-多内佩西尔混合体:设计合成和生物活性研究

Gülşah Bayraktar1, Manuela Bartolini2, Maria Laura Bolognesi2

  • 1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ege University, Izmir, Turkey.

Archiv der Pharmazie
|April 9, 2024
PubMed
概括

新的塔克林-多尼佩西尔杂交物显示出作为多目标阿尔茨海默病治疗的前景. 这些化合物抑制关键酶,保护神经元,并具有良好的生物可用性和血脑屏障透.

关键词:
通过ACHE抑制,可以抑制AChE.BBB的透性是 BBB 的透性.抑制了BChE的发生.神经保护神经保护塔克林多尼佩西尔混合动力

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