口腔炼对CPAP遵守的影响:一项前性干预研究
Peiying Huang1, Qinglai Tang1, Xinming Yang1
1Department of Otolaryngology Head and Neck Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.
口腔炼显著改善了中度至重度阻塞性睡眠呼吸暂停 (OSA) 患者的持续正气道压力 (CPAP) 遵守. 在CPAP使用和减少白天嗜睡的改善持续了六个月.
科学领域:
- 睡眠医学 睡眠医学
- 呼吸系统疗法 呼吸系统疗法
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 阻塞性睡眠呼吸暂停 (obstructive sleep apnea,OSA) 是一种常见的睡眠障碍,在睡眠期间重复出现上呼吸道崩的特征.
- 持续正气道压力 (CPAP) 是中度至重度OSA的主要治疗方法,但坚持可能是具有挑战性的.
- 口腔炼旨在加强参与气道通透的肌肉.
研究的目的:
- 评估口腔炼对中度至重度OSA患者CPAP遵守的影响.
- 评估这项干预措施在六个月的长期影响.
主要方法:
- 一项前性,观察性和干预性研究,涉及70名中度至重度OSA患者.
- 随机分配到口腔炼组 (n=44) 或假药治疗对照组 (n=26).
- 在基线,3个月和6个月测量了CPAP遵守,客观睡眠数据和爱普沃思睡眠度量得分.
主要成果:
- 口腔炼组在3个月 (5.5±1.2小时/晚) 和6个月 (6.0±1.4小时/晚) 的CPAP使用时间明显长,相比假药治疗组 (分别为4.8±1.3小时/晚和4.9±1.3小时/晚).
- 从基线到6个月的CPAP使用在运动组显著增加 (p < 0.001),但在对照组没有.
- 与假药疗法组相比,口腔炼组在3个月和6个月后在白天嗜睡 (爱普沃思嗜睡量表得分) 显著减少.
结论:
- 口腔炼可以有效地提高患有中度至重度OSA的患者的CPAP坚持.
- 改善CPAP使用时间和减少白天嗜睡的好处至少持续了六个月.
- 这种非侵入性治疗提供了一个有前途的辅助治疗,可以改善OSA管理和患者的治疗结果.
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