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Updated: Jun 28, 2025

Author Spotlight: Elucidating the Pathways of TFH Cell Differentiation in Acute LCMV Challenges
05:03

Author Spotlight: Elucidating the Pathways of TFH Cell Differentiation in Acute LCMV Challenges

Published on: April 26, 2024

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I型干扰素在慢性病毒感染中诱导了一种表观遗传学上独特的记忆B细胞子集

Lucy Cooper1, Hui Xu1, Jack Polmear1

  • 1Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC, Australia; Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.

Immunity
|April 9, 2024
PubMed
概括

慢性病毒感染会损害记忆B细胞 (MBC) 免疫力. 干扰素信号破坏了MBC的身份,但早期干预可以恢复功能,尽管效果随着时间的推移而减弱.

关键词:
B 细胞 B 细胞 B 细胞国际货币基金组织 IFN IFN在 LCMV 中,LCMV 是不典型的非典型的慢性病毒感染 慢性病毒感染表观遗传学是指表观遗传学.长时间的COVID.记忆 B 细胞 B 细胞这就是 scATAC-seqq.这就是 scRNA-seqq.

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