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Updated: Jun 28, 2025

Author Spotlight: An Integrated Workflow to Study the Promoter-Centric Spatio-Temporal Genome Architecture in Scarce Cell Populations
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Published on: April 21, 2023

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细胞系原始化中的增强器切换与eRNA,Brg1的AT和SWI/SNF招募有关

Dhurjhoti Saha1, Srinivas Animireddy1, Junwoo Lee1

  • 1Department of Epigenetics and Molecular Carcinogenesis, UT MD Anderson Center, Houston, TX 77054, USA; UT MD Anderson Cancer, Center for Cancer Epigenetics, Houston, TX 77054, USA.

Molecular cell
|April 9, 2024
PubMed
概括

增强器RNAs (eRNAs) 将SWI/SNF复合体招募到细胞类型特定的增强剂中,驱动基因转录在早期发育过程中对细胞身份至关重要. 这揭示了染色质重塑和eRNA功能之间的联系.

关键词:
布尔格1 / 斯马卡4在EpiSCs上发生了什么?在MLL3/4/4上,我们可以看到.在 RNAPIIII 中.在 SWI/SNF 中.我们的 eRNA eRNA.增强剂是一种增强剂.调解者 (Med1) 是一个调解者.这是天真的,天真的.p300/CBP/CBP 公司预先设置的初始化

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