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人体受试者细胞转差的临床实用性和诊断实施,其次是RNA测序

Shenglan Li1, Sen Zhao1, Jefferson C Sinson1

  • 1Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.

American journal of human genetics
|April 9, 2024
PubMed
概括

这项研究引入了一种使用诱导神经元 (iNeurons) 诊断遗传神经系统疾病的新RNA测序方法. 这种方法改善了与疾病相关的基因的检测,提高了罕见疾病的诊断产量.

关键词:
有关RNA测序的RNA测序在RNA-seqqq.临床上可访问的组织组织.纤维细胞细胞是什么?基因诊断 基因诊断 基因诊断诱导的神经元诱导的神经元这种异形异形是什么?神经系统疾病 神经系统疾病转录组 (transcriptome) 是一个转录组.通过转差异化转化.

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RNA-seq03:21

RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
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