杀死Trypanosoma cruzi,并通过新型的氧氨酸-亚对查加斯病的免疫反应进行增强

Ana Catarina Cristovão-Silva1, Maria Carolina Accioly Brelaz-de-Castro2, Elis Dionisio da Silva1

  • 1Laboratory of Immunopathology and Molecular Biology, Aggeu Magalhães Institute, Oswaldo Cruz Foundation, 50670-42, Recife, Pernambuco, Brazil.

PubMed
概括

研究人员开发了新的氧氨酸-醇化合物,以对抗Trypanosoma cruzi (T. cruzi),这是查加斯病的原因. 化合物LIZ311显示出显著的抗寄生虫活性和免疫调节作用,具有低的哺乳动物细胞毒性,提供了一个有前途的替代治疗方法.

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