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Updated: Jun 28, 2025

Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo
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Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo

Published on: February 5, 2021

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在DEC205向疫苗下游的树突细胞中,FcRn调节了抗原呈现

Christophe Macri1, Matthew Paxman1, Devi Jenika1

  • 1Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, 30 Flemington Rd, Parkville, The University of Melbourne, Victoria, 3010, Australia.

NPJ vaccines
|April 9, 2024
PubMed
概括

新生儿Fc受体 (FcRn) 通过通过DEC205受体改善抗原呈现,显著提高树突细胞 (DC) 疫苗的疗效. 这一发现为优化DC向疫苗提供了新的策略.

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