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从强迫性到强迫性:强迫性障碍的神经基础
Trevor W Robbins1, Paula Banca2, David Belin2
1Behavioural and Clinical Neuroscience Institute, Department of Psychology, University of Cambridge, Cambridge, UK. twr2@cam.ac.uk.
Nature reviews. Neuroscience
|April 9, 2024
概括
强迫性行为,在诸如成等疾病中见到的,源自前-上大脑电路. 了解强迫性的理解
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 行为科学 行为科学
背景情况:
- 强迫行为是神经精神疾病的跨诊断症状,例如强迫症和成.
- 强迫性是一种维度特征,代表了这些行为的一种严重表现.
研究的目的:
- 审查强迫和强迫性的心理基础.
- 检查与强迫性行为相关的神经电路.
主要方法:
- 来自人类神经成像研究的综合证据.
- 结合了来自强迫行为动物模型的发现.
主要成果:
- 识别了关键的前-上系统,涉及到目标导向的行为和习惯形成.
- 突出了轨道前额,前额,前带皮和岛屿皮层的作用.
- 强调与基底,感觉运动和顶层皮层以及小脑的连接.
结论:
- 额头-状回路是理解强迫性的核心.
- 这些发现对冲动-强迫性障碍的分类和治疗有影响.
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