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Updated: Jul 22, 2026

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
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Published on: April 20, 2018

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CHD4充当预后因素,并驱动HPV阴性HNSCC的放射电阻

Fabian Geyer1, Maximilian Geyer2, Ute Reuning3

  • 1Department of Oral and Maxillofacial Surgery, Klinikum Rechts der Isar der Technischen Universität München, 81675, Munich, Germany. ge52men@mytum.de.

Scientific reports
|April 9, 2024
PubMed
概括

CHD4的高表达预测了抗辐射HPV阴性头癌的生存率较低. 降低CHD4水平会增强癌细胞的辐射敏感性,这表明CHD4是HNSCC的治疗点.

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相关概念视频

Hazard Ratio01:12

Hazard Ratio

The hazard ratio (HR) is a widely used measure in clinical trials to compare the risk of events, such as death or disease recurrence, between two groups over time. It reflects the ratio of hazard rates—the instantaneous risk of the event occurring—between a treatment group and a control group. This measure provides valuable insights into the relative effectiveness of a treatment by assessing how the risk of an event differs between the two groups.
For example, in a clinical trial evaluating a...