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Updated: Jun 28, 2025

A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics
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脂肪乙辅酶A通过MiD49和MiD51的寡合化激活了线粒体分裂

Ao Liu1, Frieda Kage1, Asan F Abdulkareem1,2

  • 1Department of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth College, Hanover, NH, USA.

Nature cell biology
|April 9, 2024
PubMed
概括

长链合酶A (LCACA) 通过诱导寡合化来激活线粒体裂变蛋白MiD49和MiD51. 这一过程增强了DRP1的GTPase活性,揭示了脂肪酸诱导的线粒体分裂机制.

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