遵守Eatwell指南和心脏代谢,认知和神经成像参数:来自PREVENT痴呆研究的分析
Sarah Gregory1, Alex Griffiths2, Amy Jennings3,4
1Edinburgh Dementia Prevention, Outpatient Department 2, Western General Hospital, Crewe Road South, Edinburgh, EH42XU, UK. Sarah.Gregory@ed.ac.uk.
Nutrition & metabolism
|April 9, 2024
概括
英国Eatwell指南饮食在本研究中没有直接降低痴呆风险. 然而,它与降低血压和BMI有关,这是预防痴呆症的重要因素.
科学领域:
- 营养科学 营养科学
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- "Eatwell指南"提供了英国的饮食建议.
- 以前的研究将健康饮食与心血管和大脑健康联系起来.
- 没有研究探讨了Eatwell指南与痴呆风险的关联.
研究的目的:
- 调查Eatwell指南饮食模式与未来痴呆风险之间的关联.
- 检查Eatwell指南与心脏代谢和大脑健康指标之间的关系.
主要方法:
- 利用了来自PREVENT痴呆症队列研究的数据.
- 开发了二进制和分级的Eatwell指南分数 (BEWG,GEWG) 来自食物频率问卷.
- 用CAIDE评分来衡量阿尔茨海默病风险和其他健康指标;用通用添加模型进行分析.
主要成果:
- 在Eatwell指南得分和痴呆风险 (CAIDE得分) 或大脑健康之间没有发现显著的关联.
- 较高的GEWG分数与较低的静缩和静缩血压相关.
- 较高的GEWG分数与较低的身体质量指数 (BMI) 有关.
结论:
- 爱特威尔指南可能通过改善高血压和肥胖症来间接支持痴呆症预防.
- 需要进一步的研究来证实其他英国队列的发现.
- 建议对Eatwell Guide的评分方法进行改进.
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