随着时间的推移,Perceval-S. 在使用十年后的临床结果
Nikolaos Schizas1, Ilias Samiotis2, Georgia Nazou3
1Cardiovascular and Thoracic Surgery Department, Evangelismos General Hospital, Athens, Greece. nikschizas@gmail.com.
Journal of cardiothoracic surgery
|April 9, 2024
概括
佩尔塞瓦尔-S主动脉置换后的长期存活是令人满意的,生物假体功能障碍有限. 透气管大动脉置换 (TAVR) 的引入,将治疗转向了接受手术的低风险患者.
科学领域:
- 心血管外科心血管外科
- 生物假体门的使用方法
- 外科手术的结果
背景情况:
- 珀塞瓦尔-S生物假体是手术性大动脉置换 (AVR) 的广泛使用的选择.
- 虽然短期和中期疗效已经确立,但对Perceval-S的长期结果数据仍然有限.
研究的目的:
- 评估使用Perceval-S生物假体进行大动脉置换 (AVR) 的患者的长期结果.
- 在现实环境中评估生存率,生物假体功能和程序特征.
主要方法:
- 在一个大规模的心血管中心进行了一项观察性,回顾性研究.
- 收集了205名患者的数据,这些患者在2013年至2020年期间接受了Perceval-S生物假体.
主要成果:
- 在5年后的整体生存概率为64.8%.
- 在55.6%的死亡患者中,有害的心脏事件是可能的死亡原因.
- 2017年引入过导管大动脉置换 (TAVR) 导致接受Perceval-S的高风险患者数量减少,中位数EuroSCORE II显著减少.
- 在79.5%的病例中进行了小型骨切除术,并且观察到重新干预的发生率很低,患者与假肢不匹配,以及结构变性.
结论:
- 在阿动脉置换后,Perceval-S生物假体显示了令人满意的长期存活率.
- 生物假体功能障碍是罕见的,大多数手术都采用了微创性迷你椎切除方法.
- TAVR的出现影响了患者对Perceval-S的选择,导致人们转向风险较低的手术候选人.
相关概念视频
02:20Longitudinal Research
12.0K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
12.0K
01:15Nursing Evaluation
3.3K
The evaluation stage signals the end of the nursing process. The nurse gathers evaluative data to assess whether or not the patient has attained the expected results. Whereas the nurse collects data in the nursing assessment to identify the patient's health concerns, the evaluation stage data determines if the indicated health issues are resolved. Evaluative data collection includes two sections: the data acquired to evaluate patient outcomes and the time criteria for data collection.
3.3K
01:11Guidelines for Writing Outcome
2.8K
When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
2.8K
01:11Clinical Trials: Overview
2.9K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
2.9K
01:17Classification of Illness
7.5K
The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
7.5K
01:19Pharmacovigilance
830
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
830