[一个COVID-19相关的缺血性结肠炎病例]
Xin Liu1, Xueying Shi2, Jun Li1
1Department of Gastroenterology, Peking University Third Hospital, Beijing 100191, China.
概括
COVID-19可以引起缺血性结肠炎,即使在中度病例中,也会出现广泛的肠道病变. 这一案例突显了冠状病毒感染引起的高凝血性和非典型缺血性结肠炎呈现之间的联系.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 病理学 病理学 病理学
背景情况:
- 缺血性结肠炎涉及由于血液供应减少而导致肠道组织死亡,风险因素包括心血管疾病和糖尿病.
- 典型的症状是腹部疼痛和血,通常影响脏曲和直腰结.
研究的目的:
- 在患有中度COVID-19的患者中报告一种异常的缺血性结肠炎病例.
- 调查COVID-19相关高凝性在缺血性结肠炎发展中的潜在作用.
- 提高临床意识的缺血性结肠炎作为COVID-19的潜在并发症,即使在非严重的情况下.
主要方法:
- 一个中度COVID-19患者的病例报告,该患者患有缺血性结肠炎.
- 分析了临床表现,内镜发现,成像 (CT) 和病理检查.
- 进行了实验室测试,包括费里丁,D-二聚体,自身抗体和便病因学.
主要成果:
- 这位患者出现了不典型的,扩散性缺血性结肠炎,从眼到直腰结.
- 图像检查没有显示出肠道缺血的迹象,但病理检查显示小间歇性血管的血栓形成.
- 高水平的费里丁和D-二聚体,加上负的自身抗体和便病因学结果,支持了COVID-19相关高凝性诊断.
结论:
- 与COVID-19相关的高凝血性可能与缺血性结肠炎的发病有关,即使在中度病例中也是如此.
- 缺血性结肠炎可以呈现异常,广泛的病变,并且可能具有缓慢的恢复过程.
- 临床医生应该考虑COVID-19患者的缺血性结肠炎,腹痛和血,将其与与病毒直接相关的胃肠道症状区分开来.
相关概念视频
01:27Inflammatory Bowel Disease I: Ulcerative Colitis
173
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
173
01:30Inflammatory Bowel Disease II: Crohn's Disease
227
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
227
01:20COPD: Pathogenesis and Clinical Features
267
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
267
01:17Gastritis-II: Pathophysiology
322
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
322
01:17Ischemic Heart Disease: Overview
1.3K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
1.3K
01:30Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
331
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
331