时间型和轮班工作与COVID-19感染的关联
Stuart F Quan1, Matthew D Weaver, Mark É Czeisler
1From the Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts (S.F.Q., M.D.W., L.K.B., R.I.L., R.R., S.M.W.R., C.A.C.); Division of Sleep Medicine, Harvard Medical School, Boston, Massachusetts (S.F.Q., M.D.W., L.K.B., R.R., S.M.W.R., C.A.C.); Francis Weld Peabody Society, Harvard Medical School, Boston, Massachusetts (M.É.C.); School of Psychological Sciences, Turner Institute for Brain and Mental Health, Monash University, Melbourne, Australia (M.É.C., M.L.J., P.V., S.M.W.R.); Institute for Breathing and Sleep, Austin Health, Heidelberg, Australia (M.É.C., L.A.B., M.E.H., M.L.J., C.F.M.D., A.R., S.M.W.R.); University Department of Rural Health, La Trobe Rural Health School, La Trobe University, Bendigo, Australia (L.A.B.); Turner Institute for Brain and Mental Health, Monash University, Clayton, Australia (M.E.H.); Department of Medicine, The University of Melbourne, Melbourne, Australia (M.E.H., C.F.M.D., A.R.); Department of Respiratory and Sleep Medicine, Austin Health, Heidelberg, Australia (C.F.M.D., A.R.); and Faculty of Medicine, Monash University, Melbourne, Australia (C.F.M.D.).
早晨的时间型 (人体的时间型)
科学领域:
- 时间生物学 时间生物学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 时代型,一个人的自然倾向在特定时间睡觉和醒来,可能会影响感染的易感性.
- 轮班工作,特别是涉及夜班的工作,可能会扰乱昼夜节律,并可能影响健康结果.
- 了解时间型,轮班工作和COVID-19风险之间的相互作用对于公共卫生战略至关重要.
研究的目的:
- 为了调查时间型与COVID-19感染的流行率之间的关联.
- 检查与COVID-19风险有关的时间型和轮班工作之间的潜在相互作用.
主要方法:
- 来自19,821名美国成年人的横截面调查数据.
- 以人口统计,社会经济,工作,睡眠和并发症因素为准的统计分析.
- 在不同时间型 (早晨,中午,晚上) 和工作时间表中比较COVID-19感染率.
主要成果:
- 早晨的时间型与更高的COVID-19感染率有关 (aOR:1.15).
- 晚间时间型与COVID-19感染的发病率较低有关 (aOR:0.82).
- 在一些晚班工作的早晨时型个体中,观察到COVID-19感染率最高 (aOR:1.87).
结论:
- 早晨的时间型和混合轮班工作 (包括晚班) 与COVID-19感染的风险增加有关.
- 时间型和工作时间表的相互作用是了解COVID-19流行病学的重要考虑因素.
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