对牙内性病变的牙内性来源的微生物群的比较评估
Ankit Mahajan1, Mohammed Ahsan Razi2, Moumita Kundu3
1Department of Dentistry, Government Medical College, Kathua, Jammu and Kashmir, India.
Journal of pharmacy & bioallied sciences
|April 10, 2024
概括
牙周内病变 (PELs) 含有多种细菌,其中 Porphyromonas gingivalis,Treponema denticola 和 Fusobacterium nucleatum 是最常见的. 了解这种微生物特征是有效治疗PEL的关键.
科学领域:
- 微生物学 微生物学
- 牙周内科医院 牙周内科医院 牙周内科医院
- 牙周病学 牙周病学
背景情况:
- 牙周内病变 (PELs) 是由微生物菌群影响的复杂疾病.
- 识别PEL中的特定细菌对于开发有针对性的治疗策略至关重要.
研究的目的:
- 为了分析诊断PELs的牙的微生物组成.
- 为了确定这些病变中的细菌物种的流行率.
主要方法:
- 从50颗带有PEL的牙中采集了微生物样本,使用根通道中的无菌纸点.
- 使用16S核糖体RNA (rRNA) 基因的聚合酶链反应 (PCR) 来提取和放大细菌DNA.
- 对获得的数据进行了统计分析.
主要成果:
- 在PEL中发现了各种各样的细菌物种.
- 最常见的病原体包括 Porphyromonas gingivalis (32.5%),Treponema denticola (28.0%) 和 Fusobacterium nucleatum (22.5%),这些病原体是最常见的.
- 其他检测到的细菌包括Streptococcus mutans,Actinomyces naeslundii,Prevotella intermedia,Aggregatibacter actinomycetemcomitans,以及Enterococcus faecalis. 这些细菌都被发现.
结论:
- 牙周病原体具有多微生物性质,具有显著的牙周病原体存在.
- 这些发现凸显了牙周和内牙感染之间的强烈联系.
- 了解微生物特征对于开发有效的,针对病原体的治疗方法至关重要.
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