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矿物三氧化物聚合物,生物活性玻璃和以环氧树脂为基础的密封剂的抗菌有效性:一个试验室干预性研究
Saurav Kumar Dutta1, Chandra Vijay Singh2, Manoj Kumar Hans3
1Post Graduate Student, Department of Conservative Dentistry and Endodontics, Institute of Dental Sciences, Bareilly, Uttar Pradesh, India.
Journal of pharmacy & bioallied sciences
|April 10, 2024
概括
这项研究评估了根管密封剂对细菌的作用. 合成密封剂显示出对黄金葡萄球菌的最佳抗菌疗效,而MTA fillapex对Candida albicans最有效.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 微生物学 微生物学
- 牙科材料科学 牙科材料科学
背景情况:
- 根管密封器对于内牙治疗的成功至关重要.
- 评估不同类型密封剂的抗菌疗效对于临床决策至关重要.
研究的目的:
- 为了比较三种根管密封剂的体外抗菌疗效:矿物三氧化物聚合物 (MTA) fillapex,生物活性玻璃密封剂和以环氧树脂为基础的密封剂.
- 为了确定哪种海动物对金黄色葡萄球菌和白菌的抑制能力更强.
主要方法:
- 在实验室中使用Mueller Hinton亚格板进行了亚格扩散试验.
- 准备了金黄色葡萄球菌 (ATCC 6538) 和白菌 (ATCC 10231) 的标准化注射剂.
- 三种根管密封剂 (MTA fillapex,生物活性玻璃和以环氧树脂为基础的) 被放置在阿加井中,并在化后测量了抑制区域.
主要成果:
- 以环氧树脂为基础的密封剂 (Syntex) 呈现出最大的阻碍区域对金黄色葡萄球菌.
- MTA fillapex显示出对Candida albicans的最大抑制作用.
- 与其他两种密封剂相比,生物活性玻璃密封剂对两种微生物的抑制作用较小.
结论:
- 合成密封剂具有优越的抗菌活性,可以对抗黄金葡萄球菌.
- MTA fillapex对Candida albicans表现出更好的抗菌疗效.
- 密封剂的选择可能会影响内牙治疗中的抗菌结果,这取决于目标微生物.
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