一天的时间和季节分布在中风代码子类型之间:缺血性中风,内出血和中风模仿之间的差异
Alex Menéndez Albarracín1, Adrián Valls Carbó1, Neus Rabaneda Lombarte1
1Hospital Germans Trias i Pujol, Badalona, Spain.
Frontiers in neurology
|April 10, 2024
概括
这项研究揭示了中风亚型的明显日常模式,大脑内出血 (ICH) 在黎明时达到顶峰,中风在下午模仿. 脑卒中发病率显示出早上和下午的高峰,根据亚型而异.
科学领域:
- 神经学 神经学
- 时间生物学 时间生物学
- 流行病学 流行病学
背景情况:
- 循环节律影响中风症状发作,心血管风险的早晨峰值已知.
- 之前的研究发现,中风亚型之间的每日时间分布没有显著差异.
- 了解这些节奏对于预防中风和治疗策略至关重要.
研究的目的:
- 为了研究和比较缺血性中风,脑内出血 (ICH) 和中风模仿的症状发作的季节性和昼夜模式.
- 为了确定各种中风亚型的每日和季节分布的潜在差异.
主要方法:
- 一项基于医院的前性研究,从2018年到2021年对2,348名中风预警患者进行了研究.
- 患者被分为缺血性中风,ICH,暂时性缺血性攻击 (TIA) 和中风模仿组.
- 症状发作的时间被分析为4小时间隔,季节性分布每季度评估.
主要成果:
- 脑内出血 (ICH) 主要发生在凌晨4-8点之间 (黎明),通常与高血压有关.
- 脑卒中模拟器显示,晚上8点左右的高峰发作.
- 缺血性中风在一天中均分布,而TIA在下午 (12-4 PM) 达到顶峰. 在所有亚型中,冬季月份的中风病例累积最多.
结论:
- 不同的中风亚型存在不同的昼夜节律,特别是黎明时的ICH和晚上模仿的中风.
- 整体中风昼夜模式与之前的研究结果一致,显示了早晨和下午的峰值.
- 季节性变化表明冬季中风发生率较高,不管亚型如何.
相关概念视频
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