状细胞疾病与粮食不安全之间的双向关系:范围审查
Faeben Wossenseged1, Kristina Franklin2, Talya Gordon2
1Social and Behavioral Research Branch, National Institutes of Health, National Human Genome Research Institute, Bethesda, Maryland, USA.
Health equity
|April 10, 2024
概括
粮食不安全 (FI) 加剧了状细胞疾病 (SCD) 的严重程度,创造了一个有害的循环. 解决FI对于改善SCD患者的健康结果至关重要.
科学领域:
- 血液学 血液学 血液学
- 公共卫生 公共卫生
- 营养科学 营养科学
背景情况:
- 状细胞疾病 (SCD) 在美国影响了80,000-100,000人.
- 在SCD患者中营养不良会损害免疫功能,使疾病恶化.
- 粮食不安全 (FI) 被定义为无法获得足够的食物的不确定性,是营养不良的主要驱动因素.
研究的目的:
- 调查粮食不安全和状细胞疾病严重程度之间的关系.
- 了解FI如何影响SCD的病理生理学和恶化.
主要方法:
- 根据PRISMA指南进行了范围审查.
- 同行评审的文章和会议摘要被系统地搜索和审查.
- 三位独立审稿人分析了所选的研究,以进行描述性分析.
主要成果:
- 确定了SCD和FI之间的双向关系.
- 七个主要主题出现了:FI的流行,儿童/护理人员的经验,心理社会因素,食品援助,饮食摄入量,外部支出和医疗保健利用.
- 目前存在的证据有限,突出显著的研究差距.
结论:
- SCD和FI相互影响,相互恶化对方.
- 调查结果显示,在SCD人群中了解和解决FI方面存在关键差距.
- 有机会进行干预,以减轻FI和改善SCD管理.
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