在患有细菌感染性内心炎的患者中侵袭性坎迪达感染
Travis Combs1, Bobbi Jo Stoner2, Parker McCoy2
1Department of Internal Medicine, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Open forum infectious diseases
|April 10, 2024
概括
侵入性Candida感染会使细菌内心炎复杂化,特别是在有注射药物使用史和广泛抗生素暴露的患者中. 这项研究在21个月内发现了12起此类病例.
科学领域:
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
- 菌类学 菌类学是指菌类学.
背景情况:
- 细菌内心炎是一种严重的感染,影响心脏门.
- 侵入性真菌感染,特别是Candida物种,可以是机会性病原体.
- 在细菌性内心炎患者中与Candida同时感染是一种已知的但潜在的未报告的并发症.
研究的目的:
- 为了识别和描述在细菌内心炎治疗期间发生的侵入性Candida感染病例.
- 探索与这种患者群体中侵入性Candida感染的发展相关的潜在风险因素.
主要方法:
- 对21个月的医疗记录进行回顾性审查.
- 诊断出患有细菌性内心炎和侵入性Candida感染的患者的鉴定.
- 对患者人口统计,治疗方案和临床结果的分析.
主要成果:
- 在细菌内心炎治疗期间,确定了12名患有侵入性Candida感染的患者.
- 其中11名患者 (91.7%) 患有白血病 (血流中的白血病).
- 观察到的危险因素包括注射药物使用史和暴露于广谱抗生素.
结论:
- 侵入性Candida感染是细菌内心炎的一个重要并发症.
- 患有细菌性内心炎的患者,特别是有注射药物使用史和广泛抗生素暴露的患者,风险更高.
- 在这个易受伤害的患者群体中,增加对真菌共感染的警和诊断考虑是合理的.
相关概念视频
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Endocarditis I: Introduction
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Endocarditis III: Medical Management
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Endocarditis IV: Nursing Management
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Myocarditis I: Introduction
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...


