在Candida spp. 深胸部伤口感染:使用抗生素的后果?
Thomas McNeil1,2, Joanna Coats3, Santhosh Daniel1,2
1Microbiology and Infectious Diseases, Flinders Medical Centre, Adelaide, South Australia, Australia.
Open forum infectious diseases
|April 10, 2024
概括
发生了一组由Candida物种引起的深胸部伤口感染. 广泛的抗生素使用被怀疑是导致这些真菌感染的因素.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 手术部位感染 手术部位感染
背景情况:
- 深胸部伤口感染 (DSWI) 是心脏手术后的严重并发症.
- 坎迪达菌种,通常是正常植物的一部分,可以引起机会性感染.
研究的目的:
- 调查一组由Candida物种引起的深胸部伤口感染.
- 确定导致疫情爆发的潜在风险因素和来源.
主要方法:
- 对患有深胸部伤口感染的患者病例的回顾性审查.
- 流行病学调查以确定常见的来源或暴露.
- 分析机构内的抗生素使用模式.
主要成果:
- 确定了一组与Candida相关的深胸部伤口感染.
- 没有发现任何共同的环境来源来解释集群.
- 广泛的抗生素用于手术预防和治疗的显著使用.
结论:
- 广泛的抗生素使用可能会增加Candida手术部位感染的风险.
- 谨慎的抗生素管理对于预防手术后的机会性真菌感染至关重要.
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