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Updated: Jul 16, 2026

Orthotopic Xenografting of Human Luciferase-Tagged Malignant Peripheral Nerve Sheath Tumor Cells for in vivo Testing of Candidate Therapeutic Agents
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条件复制性腺病毒作为对恶性外围神经膜瘤的治疗方法

Julia A Nikrad1, Robert T Galvin1, Mackenzie M Sheehy1

  • 1Department of Pediatrics, Medical School, University of Minnesota, 420 Delaware Street SE, Mayo Mail Code 484, Minneapolis, MN 55455, USA.

Molecular therapy. Oncology
|April 10, 2024
PubMed
概括

瘤性腺病毒 (ADS) 显示出治疗神经纤维素瘤1型 (NF1) 相关的恶性外围神经膜瘤 (MPNSTs) 的前景. 这些药物选择性地向并破坏MPNST细胞,在临床前模型中延长存活率并减少瘤生长.

关键词:
MT: 定期发行 定期发行有条件复制性腺病毒 (CRAd)循环氧基因酶2 (COX2) 的作用.恶性外围神经罩瘤 (MPNST) 是一种恶性外围神经罩瘤.神经纤维素瘤第一类 (NF1)型瘤性腺病毒

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