聚乙烯微塑料和高脂肪食的联合暴露会影响斑马鱼的肠道病理损伤和微生物群
Peng Huang1, Yanqiu Hu2, Xiankai Zhang2
1Department of General Pediatric Surgery, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China.
Journal of fish biology
|April 10, 2024
概括
高脂肪料 (HFD) 和微塑料 (MPs) 一起导致严重的肠道损伤,并改变斑马鱼的肠道微生物群. 这凸显了水产养殖业中HFD和MP的综合风险.
科学领域:
- 环境科学 环境科学
- 水生毒理学 水生毒理学
- 微生物组研究 微生物组研究
背景情况:
- 微塑料 (MP) 是影响水生生态系统的普遍环境污染物.
- 高脂肪料 (HFD) 在水产养殖中通常用于促进鱼类的生长和生产.
- 没有充分了解MP和HFD对鱼类健康,特别是肠道完整性和微生物群的综合影响.
研究的目的:
- 研究高脂肪料 (HFD) 和微塑料 (MPs) 对斑马鱼肠道病理学的协同影响.
- 分析由于同时暴露于HFD和MP而导致肠道微生物组合的变化.
- 通过了解这些综合环境压力因素,为可持续的水产养殖实践提供见解.
主要方法:
- 斑马鱼被分为接受正常饮食 (ND) 或HFD的组.
- 鱼类暴露在聚钢 (PS) 微塑料 (5和50微米) 或对照环境中.
- 进行了组织病理学分析和肠道微生物组测定,以评估肠道损伤和微生物群落结构.
主要成果:
- 5μm MPs和HFD的组合诱导了斑马鱼最严重的肠道病理.
- 暴露于MP和HFD显著改变了肠道微生物组的组成和多样性.
- 较小的MP (5微米) 与HFD结合,对肠道健康产生更明显的负面影响.
结论:
- 高脂肪料和微塑料污染对水产养殖中的鱼类健康构成联合威胁.
- 饮食和微塑料暴露之间的相互作用严重影响肠道病理和肠道微生物群.
- 水产养殖管理应考虑饮食策略和微塑料污染,以确保鱼类的福利和生产.
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