1型糖尿病与饮食障碍之间的关联:系统性审查和元分析
Yomna E Dean1, Karam R Motawea1, Muaaz Aslam2
1Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Endocrinology, diabetes & metabolism
|April 10, 2024
概括
患有1型糖尿病 (T1DM) 的人患饮食障碍 (EDs) 的风险明显更高,特别是神经过敏症和过度饮食. 女性糖尿病患者也有更高的胰岛素缺失或滥用风险.
科学领域:
- 内分泌学 在内分泌学.
- 精神病学是一个精神病学.
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 以前的元分析对饮食障碍 (ED) 与1型糖尿病 (T1DM) 之间的关联产生了不确定的结果.
- 这项研究旨在分析T1DM患者中普遍存在的特定ED和饮食失调行为.
研究的目的:
- 分析T1DM与各种ED和饮食行为障碍之间的关联.
- 为了确定T1DM患者中更常见的特定ED和行为.
- 调查T1DM患者在胰岛素滥用中的性别差异.
主要方法:
- 在PubMed,Scopus和Web of Science上进行了全面的文献搜索.
- 仅包括使用关键词的观察性受控研究:"T1DM"",饮食障碍"和"Bulimia".
- 用Revman软件 (5.4版本) 进行数据分析.
主要成果:
- 与非糖尿病人相比,T1DM与ED风险增加2.47倍有关.
- 神经性食欲 (RR=2.80) 和暴饮暴食 (RR=1.53) 与T1DM有显著的相关性.
- 在T1DM中,ED的风险增加在DM验证和通用诊断问卷中持续存在.
- 胰岛素遗漏/滥用率为10.3%,糖尿病女性的风险高于男性.
结论:
- 在T1DM和ED之间存在着显著的联系,特别是食欲不良和暴饮暴食.
- 患有T1DM的女性面临更高的胰岛素滥用/遗漏风险.
- 建议早期,主动查和量身定制的干预措施,将糖尿病和ED管理结合起来,并向精神病医生转诊.
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