儿童中的加多对比剂沉积
1Department of Radiology, Key Laboratory of Obstetric and Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China.
Journal of magnetic resonance imaging : JMRI
|April 10, 2024
概括
基于加多的对比剂 (GBCA) 可以沉积在儿童的大脑中,由MRI和组织学证实. 本综述研究了儿童的加多沉积,并比较了线性与宏环性GBCA的安全性.
科学领域:
- 放射学 放射学是一门学科.
- 儿科成像学 儿科成像学
- 神经成像是一种神经成像.
背景情况:
- 基于加多的对比剂 (GBCA) 在MRI中被广泛使用.
- 研究表明,在GBCA给药后,大脑组织中的加多沉积.
- 人们对加多的保留存在担忧,特别是在儿童群体中.
研究的目的:
- 审查当前关于儿童加多沉积的研究.
- 分析使用新方法检测加多沉积的研究.
- 在儿科患者中比较线性和宏循环GBCA的安全性.
主要方法:
- 关于儿童的加多沉积现有文献的综述.
- 分析使用先进成像和组织学技术的研究.
- 对不同类型的GBCA在儿科患者群体中的安全数据的比较评估.
主要成果:
- 在儿童T1-MRI上,深层大脑核中存在加多沉积的证据.
- 组织学证实了加多在各种组织中的积累.
- 新出现的数据比较线性和宏循环GBCA在儿童中的安全性.
结论:
- 在接受GBCA的儿童中,加多沉积是一种已确认的现象.
- 需要进一步的研究才能充分理解长期影响.
- 相对的安全数据指导临床决策关于GBCA选择在儿科.
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