沉积物毒性测试:对其在环境法规中的使用进行批判性审查
Matti T Leppanen1, Sandrine Sourisseau2, Robert M Burgess3
1Finnish Environment Institute, Jyväskylä, Finland.
Environmental toxicology and chemistry
|April 10, 2024
概括
沉积物毒性测试对水生动物健康至关重要,全球法规差异很大. 已有协调的方法,但回顾性评估需要区域调整,并提高不同污染物和终点的灵活性.
科学领域:
- 环境毒理学环境毒理学
- 生态毒理学 生态毒理学
- 环境化学环境化学
- 监管科学 监管科学
背景情况:
- 沉积物是关键的水生成分,连接水的使用和服务.
- 沉积物的化学污染是一个全球性的环境问题.
- 全球的监管框架解决了前性和后性沉积物污染问题.
研究的目的:
- 审查环境法规中沉积物毒性测试的全球实施情况.
- 评估当前测试实践的协调性和区域适用性.
- 确定挑战,并建议监管沉积物毒性测试的未来改进.
主要方法:
- 关于沉积物毒性测试的全球环境法规的全面审查.
- 对前性和后性沉积物评估的协调状态的分析.
- 评估当前的毒性测试物种,协议及其限制.
主要成果:
- 沉积物毒性测试在欧盟,北美和澳大利亚最为成熟.
- 前性评估 (例如农药) 比后性评估更加协调一致.
- 通过经合组织的指导方针,国际协调力很强,但回顾性测试需要区域物种和新出现的污染物的灵活协议.
结论:
- 现有的沉积物毒性测试协议需要加强,以解决各种污染物和生态目标.
- 未来的发展应该包括体外和基因组技术,多种类的方法,以及与生态保护的更好的联系.
- 为有效的全球沉积物管理,将回顾性评估与区域特异性调整至关重要.
相关概念视频
Microbial Wastewater Treatment
Microbial communities in aquatic ecosystems play a key role in the natural breakdown of contaminants introduced through domestic and industrial effluents. Acting as biological catalysts, these microbes change and mineralize a wide range of organic and inorganic pollutants under different redox conditions.In oxygen-rich surface waters, aerobic heterotrophs lead organic matter breakdown, using oxygen as the terminal electron acceptor to efficiently oxidize substrates to carbon dioxide and water.
Toxicity Testing in Animals
Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...


