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Updated: Jun 28, 2025

Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade
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移植后的循环胺或细胞选择在平分异性的全原血造细胞移植中?

Razan Mohty1, Zaid Al Kadhimi1, Mohamed Kharfan-Dabaja2

  • 1Division of Hematology Oncology, Department of Medicine, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL, USA.

Hematology (Amsterdam, Netherlands)
|April 10, 2024
PubMed
概括

哈普罗特异性全原性造血细胞移植 (allo-HCT) 现在利用T细胞枯竭 (TCD) 或移植后环胺 (PTCy) 来克服HLA障碍并减少移植对宿主疾病 (GVHD). PTCy提供了更容易的应用和更低的成本,但潜在的毒性需要仔细考虑.

关键词:
发生相同的移植.细胞选择 细胞选择在移植后的循环胺胺.

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