追踪心血管系统生物衰老的非侵入性技术:JACC家族系列
Zahra Raisi-Estabragh1, Liliana Szabo2, Art Schuermans3
1William Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, London, United Kingdom; Barts Heart Centre, St. Bartholomew's Hospital, Barts Health NHS Trust, London, United Kingdom.
JACC. Cardiovascular imaging
|April 10, 2024
概括
人口老龄化是全球面临的一个重大挑战. 本综述探讨了生物心血管衰老的特征和非侵入性成像技术,以促进健康的衰老和延长健康寿命.
科学领域:
- 老年学和心血管医学.
背景情况:
- 人口老龄化是一个重大的人口变化,使健康寿命延长成为全球优先事项.
- 生物衰老涉及到分子和细胞的变化导致生理衰退和与年龄有关的疾病的易感性增加.
- 心血管疾病是老年人群中致病率和死亡率的主要原因.
研究的目的:
- 审查生物心血管衰老的标志.
- 讨论非侵入性成像和其他评估心血管衰老的技术.
- 探索这些信息的应用,以了解衰老轨迹,并指导健康衰老的干预措施.
主要方法:
- 关于生物衰老特征的文献综述.
- 对心血管评估的非侵入性成像技术 (如MRI,CT,超声波) 的检查.
- 分析影响个体衰老速度的因素,包括遗传和环境暴露.
主要成果:
- 确定了心血管衰老的关键分子和细胞特征.
- 突出了各种成像模式在捕捉这些衰老标记的实用性.
- 强调了个体中衰老率的变化.
结论:
- 了解心血管衰老的特征对于促进健康衰老至关重要.
- 非侵入性技术为评估生物年龄和心血管健康提供了有价值的工具.
- 这些知识可以为有针对性的干预提供信息,以改善个人和人口层面的健康状况.
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