通过使用环保pH响应酸-素纳米微囊有效控制Rhizoctonia solani
Xu Han1, Shihao Gu1, Renle Xu1
1Jiangsu Province Key Laboratory of Biomass Energy and Materials, College of Forestry, Northwest A&F University, Yangling, Shaanxi 712100, People's Republic of China.
ACS applied materials & interfaces
|April 10, 2024
概括
一种新的纳米微囊系统有效地控制了Rhizoctonia solani,提高了抗真菌化合物的性能和农业的安全性. 这种创新的配方提高了化合物的溶解性,稳定性和叶子粘附性,提供长时间的疗效和减少对环境的影响.
科学领域:
- 农业科学 农业科学
- 材料科学 材料科学 材料科学
- 菌类学 菌类学是指菌类学.
背景情况:
- 瑞佐克托尼亚·索拉尼对作物产量构成重大威胁.
- 现有的抗真菌剂通常面临着溶解性,稳定性和向传递方面的挑战.
- 开发先进的传递系统对于有效和可持续的农业疾病管理至关重要.
研究的目的:
- 开发一种安全有效的纳米微囊系统,用于控制Rhizoctonia solani.
- 通过封装来增强基于脂的三醇衍生物 (RTD) 的性能.
- 评估封装化合物的改善的抗真菌活性,稳定性和安全性.
主要方法:
- 通过酸和乳化剂OP-10的聚合构建纳米微囊系统,然后通过铁离子化.
- 在纳米微囊 (RTD@OP10-TA-Fe) 中封装一种以素为基础的三醇衍生物 (RTD).
- 评估封装效率,化合物加载,释放动力学,体外和体内抗真菌活性,现场疗效和大米苗和斑马鱼的安全性.
主要成果:
- 实现了高封装效率 (82.39%) 和负载能力 (96.49%).
- 封装改善了RTD的水溶性,稳定性和叶子粘附性.
- 与自由RTD (EC50 = 1.237 mg/L) 相比,RTD@OP10-TA-Fe显示出更高的抗真菌活性 (EC50 = 0.860 mg/L).
- 酸性条件 (pH 5.0) 显著增加了释放率.
- 实地试验显示了长时间的疗效,在RTD@OP10-TA-Fe的3周后,抗真菌率为40%,而RTD的11.11%.
- 该配方对大米幼苗和斑马鱼具有低毒性.
结论:
- 开发的RTD@OP10-TA-Fe纳米微囊系统为管理Rhizoctonia solani.提供了一个有希望的解决方案.
- 封装显著提高了活性化合物的抗真菌功效,稳定性和输送.
- 这种方法为农业疾病控制提供了更安全,更有效的替代方案,并减少了对环境的影响.
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