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Updated: Jun 28, 2025

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E3 泛基因酶 ITCH 通过隙结通过准 connexin43 进行 lysosomal 降解来负面调节细胞间通信

Max Zachrisson Totland1, Lars Mørland Knudsen1, Nikoline Lander Rasmussen1,2

  • 1Department of Molecular Oncology, Institute for Cancer Research, Oslo University Hospital, Oslo, NO-0424, Norway.

Cellular and molecular life sciences : CMLS
|April 10, 2024
PubMed
概括

E3 泛素酶 ITCH 通过增加 lysosomes 中 Connexin43 (Cx43) 的降解,促进宫癌细胞中缺口结的丧失. 这一发现揭示了在癌症中调节细胞通信的新机制.

关键词:
宫的子宫可以连接 连接 连接消灭城市的消灭.内分泌体内分泌体内分泌体内分泌体内分泌体内分泌体内分泌体内分泌体内分泌体内分泌体内分泌体内分泌在NEDD4中,它是NEDD4.

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