高收入国家代谢综合征的种族差异:系统性审查和元分析
Nicholas Kofi Adjei1,2,3, Florence Samkange-Zeeb4, Daniel Boakye4
1Department of Public Health, Policy and Systems, University of Liverpool, Waterhouse Building 2nd Floor Block F, Liverpool, L69 3GL, UK. n.adjei@liverpool.ac.uk.
代谢综合征 (MetS) 的患病率正在高收入国家上升,特别是在少数民族妇女中. 基于种族风险概况的有针对性的干预措施对于降低MetS负担至关重要.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 心血管疾病研究研究
背景情况:
- 代谢综合征 (MetS) 在全球范围内构成了重大公共卫生挑战.
- 了解MetS患病率的种族和性别差异对于有针对性的干预至关重要.
研究的目的:
- 系统量化高收入国家的高收入国家跨民族的MetS流行率差异.
- 评估从1996年到2022年的整体MetS流行趋势.
主要方法:
- 系统的文献审查 医学网,科学网,CINAHL和科克兰图书馆.
- 使用NCEP-ATP III标准对23项研究 (147756名参与者) 的聚合分析.
- 后勤回归模型用于计算不同时间段的聚合流行率估计和置信区间.
主要成果:
- 在高收入国家,整体METS患病率从24.2% (1996-2005) 增加到31.9% (2010-2021).
- 少数民族妇女表现出最高的MetS患病率 (31.7%),明显高于少数民族妇女 (22.7%).
- 在少数民族中,女性的MetS患病率高于男性,在亚洲人中观察到的最大差异.
结论:
- 在高收入国家,MetS的流行率正在惊人地增加,不成比例地影响少数民族妇女.
- 在MetS患病率上显著的种族和性别差异需要量身定制的公共卫生战略.
- 针对种族特异性风险概况的干预措施可以有效地减少MetS的负担.
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