在SARS-CoV-2感染后,潜在可预防住院的风险
Diana J Govier1,2, Meike Niederhausen1,2, Yumie Takata3
1Center to Improve Veteran Involvement in Care, Veterans Affairs (VA) Portland Health Care System, Portland, Oregon.
JAMA network open
|April 10, 2024
概括
患有SARS-CoV-2 (严重急性呼吸系统综合征冠状病毒2) 的退伍军人患有可预防住院的风险明显更高. 这种增加的风险在感染后至少持续了一年,强调需要更好的感染后护理策略.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 医疗保健服务研究 医疗服务研究
背景情况:
- 研究表明,SARS-CoV-2 (严重急性呼吸系统综合征冠状病毒2) 感染增加了住院的风险.
- 然而,SARS-CoV-2与可能可预防的住院治疗之间的关联仍未得到充分研究.
- 潜在可预防的住院治疗是针对在门诊机构中可管理的情况.
研究的目的:
- 调查SARS-CoV-2感染与可能可预防的住院治疗之间的关联.
- 这项研究的重点是美国退伍军人全国队列.
- 目的是比较感染者与未感染者之间的住院风险.
主要方法:
- 使用模拟目标随机试验的队列研究设计.
- 包括189,136名美国退伍军人感染SARS-CoV-2和943,084名退伍军人卫生管理局 (VHA) 的匹配对比器.
- 扩展的考克斯模型分析了诊断后0-365天内潜在可预防住院的调整危险比率 (AHR).
主要成果:
- 这项研究分析了1,132,220名参与者,主要是男性退伍军人,年龄为60.3岁.
- 3.81%的SARS-CoV-2阳性退伍军人经历了可预防的住院治疗,而2.96%的比较者在1年内.
- 在感染后的30,90,180,365天观察到可预防住院的AHR显著增加.
结论:
- 在退伍军人中,SARS-CoV-2感染与可预防住院的持续,增加的风险有关.
- 这凸显了研究SARS-CoV-2如何影响感染后护理要求的必要性.
- 在SARS-CoV-2感染后制定减轻可预防住院治疗的策略至关重要.
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